Description

Ethyl 7-Chloro-3-Hydroxybenzo[B]Thiophene-2-Carboxylate is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is specifically engineered to serve as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic small molecules.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its benzo[b]thiophene core.
• Material Science Research: Serves as a building block for creating organic semiconductors, liquid crystals, and advanced polymers with specific electronic or photonic properties.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments due to the chromophoric properties of the substituted thiophene ring.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and heterocycle functionalization.
• Custom Synthesis: Provides a versatile scaffold for contract manufacturing organizations (CMOs) to produce bespoke compounds for client-specific projects.

Basic Information

Product Name	Ethyl 7-Chloro-3-Hydroxybenzo[B]Thiophene-2-Carboxylate
CAS No.	1825392-01-5
Molecular Formula	C11H9ClO3S
Molecular Weight	256.70 g/mol
Synonyms	Ethyl 7-chloro-3-hydroxy-1-benzothiophene-2-carboxylate; 7-Chloro-3-hydroxybenzo[b]thiophene-2-carboxylic acid ethyl ester; 2-Carbethoxy-7-chloro-3-hydroxybenzo[b]thiophene; Benzo[b]thiophene-2-carboxylic acid, 7-chloro-3-hydroxy-, ethyl ester; 1-Benzothiophene-2-carboxylic acid, 7-chloro-3-hydroxy-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 7-Chloro-3-Hydroxybenzo[B]Thiophene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container must be kept tightly sealed to protect the contents from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.