Description

2H-Indol-2-One, 5-Amino-6-Fluoro-1,3-Dihydro- is a high-purity, fluorinated indole derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its unique fluorinated indole structure.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and exploring new chemical reactions.
• Biochemical Probe Development: Serves as a precursor for fluorescent dyes or molecular probes used in biochemical assays and diagnostic research.
• Material Science Precursor: Potential use in the synthesis of advanced organic electronic materials and specialty polymers.

Basic Information

Product Name	2H-Indol-2-One, 5-Amino-6-Fluoro-1,3-Dihydro-
CAS No.	1824465-74-8
Molecular Formula	C8H7FN2O
Molecular Weight	166.15 g/mol
Synonyms	5-Amino-6-fluoro-1,3-dihydro-2H-indol-2-one; 6-Fluoro-5-aminooxindole; 5-Amino-6-fluorooxindole; 5-Amino-6-fluoro-2-indolinone; 2H-Indol-2-one, 5-amino-6-fluoro-1,3-dihydro-; 1824465-74-8; 5-Amino-6-fluoroindolin-2-one; 6-Fluoro-5-amino-2-oxindole
EINECS	Contact for details

Quality Control

Our 2H-Indol-2-One, 5-Amino-6-Fluoro-1,3-Dihydro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.