Description

2-tert-Butyl 8-Methyl 3,4-Dihydroisoquinoline-2,8(1H)-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the dihydroisoquinoline class of compounds. This compound is of significant value for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and oncology research.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex molecular architectures due to its functionalized dihydroisoquinoline core.
• Research & Development (R&D): Essential for academic and industrial R&D labs exploring new chemical entities and reaction pathways.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for potential drug candidates during pre-clinical and clinical development phases.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in API manufacturing.

Basic Information

Product Name	2-tert-Butyl 8-Methyl 3,4-Dihydroisoquinoline-2,8(1H)-Dicarboxylate
CAS No.	1824285-72-4
Molecular Formula	C17H23NO4
Molecular Weight	305.37 g/mol
Synonyms	2-(tert-Butyl) 8-methyl 1,2,3,4-tetrahydroisoquinoline-2,8-dicarboxylate; 2-tert-Butyl 8-methyl 1,2,3,4-tetrahydroisoquinoline-2,8-dicarboxylate; 2-(tert-Butoxycarbonyl)-8-(methoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline; 2-Boc-8-COOMe-tetrahydroisoquinoline; 2-(tert-Butyloxycarbonyl)-8-methyloxycarbonyl-3,4-dihydroisoquinoline; 1824285-72-4; tert-Butyl 8-methyl 1,2,3,4-tetrahydroisoquinoline-2,8-dicarboxylate
EINECS	Contact for details

Quality Control

Our 2-tert-Butyl 8-Methyl 3,4-Dihydroisoquinoline-2,8(1H)-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.