Description

8-Fluoroisoquinoline-4-Carboxylic Acid is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its role as a key precursor in the development of novel pharmaceutical agents and agrochemicals, where the introduction of fluorine atoms can dramatically alter biological activity and metabolic stability. It is primarily sought by research institutions and industrial R&D departments focused on medicinal chemistry, particularly for creating libraries of bioactive molecules targeting various disease pathways.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs) with potential applications in oncology, neurology, and anti-infective therapies.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates.
• Agrochemical Development: Serves as a precursor for novel herbicides, fungicides, and insecticides, leveraging the fluorine moiety for enhanced efficacy.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science: Potential intermediate for creating advanced organic electronic materials or specialty polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development projects for global clients.

Basic Information

Product Name	8-Fluoroisoquinoline-4-Carboxylic Acid
CAS No.	1824276-14-3
Molecular Formula	C₁₀H₆FNO₂
Molecular Weight	191.16 g/mol
Synonyms	8-Fluoro-4-isoquinolinecarboxylic acid; 8-Fluoro-isoquinoline-4-carboxylic acid; 4-Carboxy-8-fluoroisoquinoline; 8-Fluoroisoquinoline-4-carboxylic acid; 1824276-14-3; 8-Fluoro-1-azanaphthalene-4-carboxylic acid; 8-Fluoro-4-isoquinoline carboxylic acid; 8-Fluoro-4-carboxyisoquinoline
EINECS	Contact for details

Quality Control

Our 8-Fluoroisoquinoline-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support custom synthesis to meet specific purity or packaging requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the original container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.