Description

7-Methoxy-8-Nitro-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is a high-purity, synthetically derived organic compound belonging to the tetrahydroisoquinoline class, serving as a critical advanced intermediate in modern pharmaceutical research and development. Its value lies in its functionalized structure, which provides a versatile scaffold for constructing complex molecules with potential biological activity. This compound is primarily needed by pharmaceutical companies, contract research organizations (CROs), and academic laboratories engaged in the synthesis of novel drug candidates, particularly within medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of diverse chemical libraries for screening.
• Neurological & CNS Research: Potential intermediate in the development of compounds targeting central nervous system disorders, given the tetrahydroisoquinoline pharmacophore.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for synthetic methodology development and bioorganic studies.

Basic Information

Product Name	7-Methoxy-8-Nitro-1,2,3,4-Tetrahydroisoquinoline Hydrochloride
CAS No.	1824065-43-1
Molecular Formula	C₁₀H₁₃ClN₂O₃
Molecular Weight	244.67 g/mol
Synonyms	7-Methoxy-8-nitro-1,2,3,4-tetrahydroisoquinoline HCl; 8-Nitro-7-methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride; 1,2,3,4-Tetrahydro-7-methoxy-8-nitroisoquinoline hydrochloride; 7-Methoxy-8-nitro-1,2,3,4-tetrahydroisoquinoline monohydrochloride; 1824065-43-1; 7-Methoxy-8-nitro-THIQ HCl
EINECS	Contact for details

Quality Control

Our 7-Methoxy-8-Nitro-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.