Description

2-Fluoro-4-Methyl-3-(Trifluoromethyl)Benzyl Bromide is a high-value, multi-functional benzyl bromide derivative, distinguished by its unique fluorine and trifluoromethyl substituents. This compound is a critical building block in advanced organic synthesis, prized for its ability to introduce a reactive benzyl bromide moiety into complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, as well as by manufacturers of specialty materials and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystal compounds for advanced display technologies.
• Functional Material Development: Employed in creating specialty polymers, organic semiconductors, and other advanced materials requiring specific fluorinated aromatic units.
• Cross-Coupling Reactions: Acts as an efficient electrophile in various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to form carbon-carbon bonds.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic methodologies and constructing complex heterocyclic systems.

Basic Information

Product Name	2-Fluoro-4-Methyl-3-(Trifluoromethyl)Benzyl Bromide
CAS No.	1824048-80-7
Molecular Formula	C10H7BrF4
Molecular Weight	287.06 g/mol
Synonyms	1-(Bromomethyl)-2-fluoro-4-methyl-3-(trifluoromethyl)benzene; α-Bromo-2-fluoro-4-methyl-3-(trifluoromethyl)toluene; (2-Fluoro-4-methyl-3-(trifluoromethyl)phenyl)methyl bromide; 2-Fluoro-4-methyl-3-trifluoromethylbenzyl bromide; 3-(Trifluoromethyl)-2-fluoro-4-methylbenzyl bromide
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-Methyl-3-(Trifluoromethyl)Benzyl Bromide is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.