Description

tert-Butyl (5-Bromothiazol-4-Yl)Carbamate CAS NO 1823881-74-8 is a high-purity, advanced pharmaceutical intermediate characterized by its bromothiazole core and tert-butyloxycarbonyl (Boc) protecting group. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and antiviral drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting kinase inhibition.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic targets.
• Protease Inhibitor Development: Serves as a precursor in the creation of protease inhibitors for antiviral and anticancer applications.
• Chemical Biology Probes: Employed in the development of molecular probes to study biological pathways and protein functions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.
• Agrochemical Research: Potential use as an intermediate in the development of new active ingredients for crop protection.

Basic Information

Product Name	tert-Butyl (5-Bromothiazol-4-Yl)Carbamate
CAS No.	1823881-74-8
Molecular Formula	C8H11BrN2O2S
Molecular Weight	279.16 g/mol
Synonyms	5-Bromo-4-(((tert-butoxycarbonyl)amino)thiazole; 4-Thiazolamine, 5-bromo-N-[(1,1-dimethylethoxy)carbonyl]-; tert-Butyl N-(5-bromo-1,3-thiazol-4-yl)carbamate; Boc-5-Bromothiazol-4-amine; (5-Bromo-thiazol-4-yl)-carbamic acid tert-butyl ester; 5-Bromo-4-((Boc-amino)thiazole; 1823881-74-8; tert-Butyl 5-bromothiazol-4-ylcarbamate
EINECS	Contact for details

Quality Control

Our production of tert-Butyl (5-Bromothiazol-4-Yl)Carbamate adheres to stringent quality management protocols. Each batch is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all critical quality attributes. We support development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.