Description

8-Hydroxy-Isoquinoline-5-Carboxylic Acid is a high-purity, multifunctional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique structural framework, which serves as a critical precursor in the development of novel pharmaceutical agents and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition or receptor modulation.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic core.
• Ligand Synthesis: Serves as a precursor for chelating agents and metal-organic frameworks (MOFs) due to the presence of both hydroxy and carboxylic acid functional groups.
• Material Science: Employed in the creation of organic electronic materials, dyes, and pigments where the isoquinoline scaffold imparts specific electronic properties.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags or molecular probes in biochemical research.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory synthesis in university and CRO laboratories.

Basic Information

Product Name	8-Hydroxy-Isoquinoline-5-Carboxylic Acid
CAS No.	1823359-54-1
Molecular Formula	C10H7NO3
Molecular Weight	189.17 g/mol
Synonyms	5-Carboxy-8-hydroxyisoquinoline; 8-Hydroxy-5-isoquinolinecarboxylic Acid; Isoquinoline-5-carboxylic acid, 8-hydroxy-; 8-Hydroxyisoquinoline-5-carboxylic acid; 1823359-54-1; 8-Hydroxy-1-azanaphthalene-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 8-Hydroxy-Isoquinoline-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (HPLC), related substances, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.