Description

4-Chloroisoquinoline-8-Carboxylic Acid is a high-purity, synthetically valuable organic building block. This compound matters as a key intermediate in the research and development of novel active pharmaceutical ingredients (APIs) and advanced materials. It is primarily needed by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers for constructing complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition and other therapeutic pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require the isoquinoline scaffold.
• Material Science: Serves as a building block for creating organic ligands in catalysis and for the synthesis of advanced polymers with specific electronic properties.
• Chemical Synthesis: Employed in academic and industrial research for the construction of complex fused heterocyclic systems due to its reactive chlorinated quinoline and carboxylic acid functional groups.
• Bioconjugation & Probe Development: The carboxylic acid moiety allows for coupling to amines, making it useful for creating fluorescent probes or bioconjugates for biochemical studies.

Basic Information

Product Name	4-Chloroisoquinoline-8-Carboxylic Acid
CAS No.	1823324-56-6
Molecular Formula	C10H6ClNO2
Molecular Weight	207.61 g/mol
Synonyms	8-Carboxy-4-chloroisoquinoline; 4-Chloro-8-isoquinolinecarboxylic Acid; 4-Chloroisoquinoline-8-carboxylic acid; 1823324-56-6; 4-Chloro-8-carboxyisoquinoline; 4-Cl-IQC; 4-Chloro-8-isoquinoline carboxylic acid; 4-Chloro-8-quinolinecarboxylic acid (related structural isomer)
EINECS	Contact for details

Quality Control

Our 4-Chloroisoquinoline-8-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.