Description

2-Iodo-3-(Iodomethyl)But-1-Ene is a specialized diiodinated organic building block of significant interest in advanced synthetic chemistry. This compound matters for its unique bifunctional reactivity, offering two distinct iodine handles for sequential cross-coupling or substitution reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications in medicinal chemistry, ligand synthesis, and the development of novel functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates, particularly in structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators requiring complex alkyl-iodide motifs.
• Material Science Building Block: Employed in the creation of specialized monomers for polymers, liquid crystals, and organic electronic materials via metal-catalyzed coupling reactions.
• Cross-Coupling Reactions: Acts as a versatile substrate in palladium-catalyzed reactions such as Suzuki, Negishi, and Sonogashira couplings to introduce functionalized alkene chains.
• Chemical Biology Probes: Useful for the synthesis of molecular probes and tags for studying biological systems due to the reactivity of the iodine atoms.
• Organic Synthesis Reagent: Provides a strategic diiodo-alkene unit for cyclization reactions and the synthesis of complex natural product analogs.

Basic Information

Product Name	2-Iodo-3-(Iodomethyl)But-1-Ene
CAS No.	1822796-72-4
Molecular Formula	C5H8I2
Molecular Weight	337.92 g/mol
Synonyms	3-(Iodomethyl)-2-iodobut-1-ene; 1-Butene, 2-iodo-3-(iodomethyl)-; But-1-ene-3-(iodomethyl)-2-iodo; 2-Iodo-3-iodomethyl-1-butene; Diiodo-butene derivative; Bifunctional iodoalkene; Iodinated C5 building block
EINECS	Contact for details

Quality Control

Our 2-Iodo-3-(Iodomethyl)But-1-Ene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical synthetic work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its light-sensitive nature, the container should be amber-colored or kept in secondary opaque packaging. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.