Description

(3-Iodo-1H-Indazol-6-Yl)Methanamine is a high-purity, functionalized indazole derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block for the development of novel pharmaceutical candidates and bioactive molecules, particularly in medicinal chemistry research. Its unique structure, featuring both an iodine substituent and a primary amine group, makes it a versatile intermediate for cross-coupling reactions and further derivatization. Researchers and process chemists in the pharmaceutical, agrochemical, and life science industries require this specific scaffold to accelerate their discovery and development pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs, especially kinase inhibitors and other enzyme modulators.
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Serves as a building block for creating novel active ingredients with potential herbicidal or insecticidal properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Material Science Research: Potential intermediate for synthesizing specialized organic ligands or functional components in advanced materials.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, or Buchwald-Hartwig amination.

Basic Information

Product Name	(3-Iodo-1H-Indazol-6-Yl)Methanamine
CAS No.	1820712-10-4
Molecular Formula	C8H8IN3
Molecular Weight	273.08 g/mol
Synonyms	6-(Aminomethyl)-3-iodo-1H-indazole; 1H-Indazol-6-ylmethanamine, 3-iodo-; (3-Iodo-1H-indazol-6-yl)methanamine; 3-Iodo-1H-indazole-6-methanamine; 6-Aminomethyl-3-iodoindazole; 3-Iodo-6-aminomethylindazole; 3-Iodoindazole-6-methylamine
EINECS	Contact for details

Quality Control

Our (3-Iodo-1H-Indazol-6-Yl)Methanamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements, including custom purity grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.