Description

2-(2,6-Dimethylphenyl)-2,2-difluoroethan-1-ol is a specialized fluorinated aromatic alcohol building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines a sterically hindered dimethylphenyl group with a difluoroethanol moiety, making it a valuable precursor for creating novel materials and active pharmaceutical ingredients (APIs). Industries such as pharmaceutical R&D, agrochemical development, and specialty chemical manufacturing need this high-purity intermediate to drive innovation in their product pipelines.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides and herbicides, where the difluoro group can improve biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Specialty Polymer Modifier: Incorporated into polymer chains to alter physical properties such as solubility, thermal stability, and surface characteristics.
• Ligand & Catalyst Development: Utilized in organometallic chemistry to create novel ligands for catalytic systems.
• Fluorine Chemistry Research: A valuable substrate for academic and industrial research exploring new fluorination reactions and methodologies.

Basic Information

Product Name	2-(2,6-Dimethylphenyl)-2,2-difluoroethan-1-ol
CAS No.	1820710-55-1
Molecular Formula	C10H12F2O
Molecular Weight	186.20 g/mol
Synonyms	2,2-Difluoro-2-(2,6-dimethylphenyl)ethanol; α,α-Difluoro-2,6-dimethylbenzeneethanol; 1-(2,6-Dimethylphenyl)-2,2-difluoroethan-1-ol; (2,6-Dimethylphenyl)difluoromethyl carbinol; DFMPE; 2,6-Dimethyl-α,α-difluorobenzyl alcohol
EINECS	Contact for details

Quality Control

Our 2-(2,6-Dimethylphenyl)-2,2-difluoroethan-1-ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.