Description

7-Methoxy-6-Nitro-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is a high-purity, synthetically valuable organic intermediate in its stable salt form. This compound is of significant interest for its role as a key building block in the research and development of novel pharmaceutical agents, particularly within medicinal chemistry programs. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for synthesizing complex molecules with potential therapeutic applications.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, particularly those targeting the central nervous system.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing libraries of novel compounds for biological screening and structure-activity relationship (SAR) studies.
• Process Chemistry Development: Used in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes to study enzyme function and receptor interactions.
• Academic Research: A valuable reagent for universities and research institutions conducting studies in organic synthesis and heterocyclic chemistry.
• Custom Synthesis: The starting point for contract research and manufacturing organizations (CROs/CMOs) to produce bespoke compounds for client projects.

Basic Information

Product Name	7-Methoxy-6-Nitro-1,2,3,4-Tetrahydroisoquinoline Hydrochloride
CAS No.	1820687-16-8
Molecular Formula	C₁₀H₁₃ClN₂O₃
Molecular Weight	244.67 g/mol
Synonyms	6-Nitro-7-methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride; 7-Methoxy-6-nitro-1,2,3,4-tetrahydroisoquinoline HCl; 1,2,3,4-Tetrahydro-7-methoxy-6-nitroisoquinoline hydrochloride; 1820687-16-8; 7-Methoxy-6-nitro-3,4-dihydro-1H-isoquinoline hydrochloride
EINECS	Contact for details

Quality Control

Our 7-Methoxy-6-Nitro-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards. Custom purity grades and analytical packages are available to meet specific research or GMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture uptake. Recommended storage temperature is between 2°C and 8°C for extended stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.