Description

2-tert-Butoxycarbonylamino-4,5,6,7-Tetrahydro-Benzothiazole-6-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate of significant importance in modern organic synthesis. This compound is valued for its role as a key building block in the development of complex, biologically active molecules, particularly within medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel therapeutic agents, where precise chemical structure and reliable purity are critical for successful outcomes.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially those targeting the central nervous system.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in drug discovery programs, enabling structure-activity relationship (SAR) studies.
• Peptidomimetic Synthesis: Used in the design and synthesis of peptidomimetics, where the benzothiazole core mimics peptide structures for enhanced metabolic stability.
• Chemical Biology Probes: Employed in the development of specialized probes and tool compounds for investigating biological pathways and target validation.
• Custom Synthesis Projects: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client-specific applications.

Basic Information

Product Name	2-tert-Butoxycarbonylamino-4,5,6,7-Tetrahydro-Benzothiazole-6-Carboxylic Acid Ethyl Ester
CAS No.	1820647-12-8
Molecular Formula	C15H22N2O4S
Molecular Weight	326.41 g/mol
Synonyms	Boc-Amino-Tetrahydrobenzothiazole Ethyl Ester; Ethyl 2-((tert-Butoxycarbonyl)amino)-4,5,6,7-tetrahydrobenzo[d]thiazole-6-carboxylate; 6-Carbethoxy-2-Boc-amino-4,5,6,7-tetrahydrobenzothiazole; 2-Boc-amino-6-ethoxycarbonyl-4,5,6,7-tetrahydrobenzothiazole; 2-(N-Boc-amino)-4,5,6,7-tetrahydrobenzothiazole-6-carboxylic acid ethyl ester; 1820647-12-8; Boc-protected tetrahydrobenzothiazole derivative
EINECS	Contact for details

Quality Control

Our production of 2-tert-Butoxycarbonylamino-4,5,6,7-Tetrahydro-Benzothiazole-6-Carboxylic Acid Ethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical applications. All material is characterized and released against comprehensive specifications, including identity confirmation by spectroscopic methods and purity assessment by chromatographic techniques. Certificates of Analysis (COA) detailing all test results are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; therefore, the container should be kept tightly sealed when not in use to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.