Description

(1-Chloroisoquinolin-6-Yl)Methanol is a high-purity, advanced pharmaceutical intermediate characterized by its unique isoquinoline scaffold. This compound matters for its critical role as a versatile building block in the synthesis of complex bioactive molecules, enabling the development of new therapeutic agents. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for developing candidates in oncology and central nervous system (CNS) drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Organic Synthesis Building Block: Employed in the construction of complex heterocyclic compounds and fine chemicals due to its reactive chloromethyl and isoquinoline groups.
• Agrochemical Development: Potential application as an intermediate in the research and synthesis of new active ingredients for crop protection.
• Academic & Industrial R&D: Utilized in chemical libraries for high-throughput screening and the development of new synthetic methodologies.

Basic Information

Product Name	(1-Chloroisoquinolin-6-Yl)Methanol
CAS No.	1820640-22-9
Molecular Formula	C₁₀H₈ClNO
Molecular Weight	193.63 g/mol
Synonyms	6-(Hydroxymethyl)-1-chloroisoquinoline; 1-Chloro-6-(hydroxymethyl)isoquinoline; (1-Chloro-6-isoquinolinyl)methanol; 1-Chloroisoquinoline-6-methanol; (1-Chloro-6-isoquinolyl)methanol; 1-Chloro-6-isoquinolinemethanol
EINECS	Contact for details

Quality Control

Our (1-Chloroisoquinolin-6-Yl)Methanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure product stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.