Description

Benzeneethanol, β,β-Difluoro-4-Nitro- is a specialized fluorinated nitro-aromatic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines a fluorinated ethanol side chain with a nitro-substituted benzene ring, enabling precise modifications to target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the design and synthesis of next-generation herbicides and pesticides where the fluorine atoms enhance biological activity and metabolic stability.
• Material Science Precursor: Serves as a building block for specialty polymers and liquid crystals, where the nitro and fluorine groups influence electronic properties.
• Chemical Biology Probes: Employed in the synthesis of fluorinated probes and tags for studying biological mechanisms and protein interactions.
• Organic Synthesis Research: A versatile reagent for exploring novel fluorination reactions and constructing complex aromatic systems in academic and industrial R&D.

Basic Information

Product Name	Benzeneethanol, β,β-Difluoro-4-Nitro-
CAS No.	1818412-05-3
Molecular Formula	C8H7F2NO3
Molecular Weight	203.14 g/mol
Synonyms	2,2-Difluoro-2-(4-nitrophenyl)ethanol; 4-Nitro-α,α-difluorophenethyl alcohol; 1-(4-Nitrophenyl)-2,2-difluoroethan-1-ol; (4-Nitrophenyl)difluoroethanol; β,β-Difluoro-4-nitrophenethyl alcohol; 2-(4-Nitrophenyl)-2,2-difluoroethanol
EINECS	Contact for details

Quality Control

Our Benzeneethanol, β,β-Difluoro-4-Nitro- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.