Description

(1S,2S)-Rel-2-(5-Bromothiophen-2-Yl)Cyclopropane-1-Carboxylic Acid is a high-purity, chiral cyclopropane derivative that serves as a critical synthetic intermediate. Its value lies in the precise stereochemistry and functional groups, enabling the construction of complex molecular architectures with defined three-dimensional orientation. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of chiral drug candidates, especially in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in creating advanced, stereospecific pesticides and herbicides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of novel organic electronic materials and liquid crystals due to its rigid, conjugated structure.
• Chemical Biology Probes: Useful for creating tagged molecular probes to study biological pathways and enzyme mechanisms.
• Custom Synthesis and Scale-Up: Available for contract research organizations (CROs) and CDMOs for custom synthesis projects from gram to kilogram scale.

Basic Information

Product Name	(1S,2S)-Rel-2-(5-Bromothiophen-2-Yl)Cyclopropane-1-Carboxylic Acid
CAS No.	1818257-71-4
Molecular Formula	C8H7BrO2S
Molecular Weight	247.11 g/mol
Synonyms	(1S,2S)-2-(5-Bromo-2-thienyl)cyclopropanecarboxylic Acid; rel-(1S,2S)-2-(5-Bromothiophen-2-yl)cyclopropane-1-carboxylic Acid; (1S,2S)-2-(5-Bromothien-2-yl)cyclopropanecarboxylic Acid; trans-2-(5-Bromothiophen-2-yl)cyclopropanecarboxylic Acid (rel); 2-(5-Bromo-2-thienyl)cyclopropanecarboxylic Acid, (1S,2S)-rel-; BRD-K77925030-001-01-9; 1818257-71-4
EINECS	Contact for details

Quality Control

Our production of (1S,2S)-Rel-2-(5-Bromothiophen-2-Yl)Cyclopropane-1-Carboxylic Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We employ advanced analytical techniques including HPLC, GC, NMR, and chiral chromatography to meet the exacting standards required for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.