Description

6-Bromo-3-Pyridinylboronic Acid Mida Ester is a specialized, protected boronic acid derivative designed for enhanced stability and controlled reactivity in advanced synthetic chemistry. This compound is a critical building block for the efficient and selective construction of complex heterocyclic molecules, particularly in cross-coupling reactions. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heterobiaryl scaffolds found in drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific pyridine-based architectures.
• Material Science Research: Employed in the synthesis of organic ligands for catalysts, metal-organic frameworks (MOFs), and organic electronic materials.
• Chemical Biology Probes: Serves as a building block for creating tagged molecules and inhibitors used in proteomics and target identification studies.
• Process Chemistry & Scale-up: The Mida ester protection offers superior stability, making it suitable for multi-step synthesis and larger-scale manufacturing processes.

Basic Information

Product Name	6-Bromo-3-Pyridinylboronic Acid Mida Ester
CAS No.	1816951-75-3
Molecular Formula	C9H10BBrN2O2
Molecular Weight	269.91 g/mol
Synonyms	6-Bromo-3-pyridylboronic acid MIDA ester; (6-Bromopyridin-3-yl)boronic acid MIDA ester; 2-[(6-Bromopyridin-3-yl)-1,3,2-dioxaborolan-2-yl]-N-methyliminodiacetic acid ester; N-Methyliminodiacetic Acid (6-Bromo-3-pyridinyl)boronate; 6-Bromo-3-pyridinylboronic acid N-methyliminodiacetic acid ester; MIDA Boronate of 6-Bromo-3-pyridinylboronic Acid; 6-Bromo-3-pyridyl MIDA boronate
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Pyridinylboronic Acid Mida Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your R&D and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.