Description

4-Chloro-4''-Fluorobutyrophenone-D4 is a high-purity, deuterated organic compound primarily used as a critical intermediate in advanced chemical synthesis. Its value lies in its role as a building block for the development of isotopically labeled molecules, which are essential for research and analytical applications. This product is particularly needed by pharmaceutical R&D laboratories, agrochemical developers, and analytical service providers engaged in metabolic studies, tracer analysis, and the synthesis of novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of deuterated active pharmaceutical ingredients (APIs) and drug metabolites.
• Analytical Reference Standard: Used as an internal standard in quantitative mass spectrometry (LC-MS, GC-MS) for accurate bioanalysis and pharmacokinetic studies.
• Metabolic Tracer: Enables tracking and elucidation of metabolic pathways in biological systems due to its stable deuterium labels.
• Agrochemical Research: Intermediate in the development of novel, isotopically labeled pesticides and herbicides for environmental fate studies.
• Material Science: Potential precursor for specialty polymers or liquid crystals requiring specific fluorinated and chlorinated aromatic components.
• Chemical Synthesis: Versatile synthon for organic chemists exploring new reactions involving halogenated ketones and fluorinated aromatics.

Basic Information

Product Name	4-Chloro-4''-Fluorobutyrophenone-D4
CAS No.	1814904-27-2
Molecular Formula	C10H5D4ClFO
Molecular Weight	200.65 g/mol (Calculated)
Synonyms	1-(4-Chlorophenyl)-4-(4-fluorophenyl)-1,4-butanedione-d4; 4-Chloro-4'-fluorodibenzoylmethane-d4; 4-Chloro-4'-fluorobenzoylacetophenone-d4; 4-Chloro-4'-fluorobenzylideneacetophenone-d4 precursor; Deutero-4-Chloro-4'-fluorobutyrophenone; [D4]-4-Chloro-4'-fluorobutyrophenone; 4-Chloro-4'-fluorodibenzoylmethane, deuterated; 4'-Fluoro-4-chlorobutyrophenone-d4
EINECS	Contact for details

Quality Control

Our 4-Chloro-4''-Fluorobutyrophenone-D4 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and isotopic enrichment, meeting the stringent requirements for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC/NMR), isotopic purity (D-content), and identification data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.