Description

4-Bromo-2-Chloro-5-(Trifluoromethyl)Benzyl Alcohol is a high-value, multi-functional aromatic building block featuring bromine, chlorine, and trifluoromethyl substituents. This compound matters for its role as a versatile intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors where its unique halogenated and fluorinated structure imparts desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and advanced materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, especially in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Building block for next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the halogen and trifluoromethyl groups.
• Liquid Crystal & OLED Materials: Used in the research and production of advanced electronic display materials due to its aromatic and halogenated structure.
• Organic Synthesis & Catalysis: Serves as a precursor for ligands or complex molecules in cross-coupling reactions and other catalytic processes.
• Chemical Research (R&D): A valuable reagent for academic and industrial research exploring new chemical entities and reaction pathways.
• Fluorinated Compound Libraries: Used in combinatorial chemistry and medicinal chemistry for creating libraries of fluorinated compounds for screening.

Basic Information

Product Name	4-Bromo-2-Chloro-5-(Trifluoromethyl)Benzyl Alcohol
CAS No.	1809161-59-8
Molecular Formula	C8H5BrClF3O
Molecular Weight	289.48 g/mol
Synonyms	(4-Bromo-2-chloro-5-(trifluoromethyl)phenyl)methanol; 1-(Bromomethyl)-2-chloro-4-(trifluoromethyl)benzene-5-ol; α-Bromo-2-chloro-α-(trifluoromethyl)benzyl alcohol; 4-Bromo-2-chloro-α-(trifluoromethyl)benzenemethanol; 5-(Hydroxymethyl)-2-bromo-1-chloro-4-(trifluoromethyl)benzene; 2-Chloro-4-bromo-α-(trifluoromethyl)benzyl alcohol
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Chloro-5-(Trifluoromethyl)Benzyl Alcohol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent quality suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.