Description

Benzyl 4-((5-Bromo-1H-Indol-1-Yl)Methyl)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate designed for research and development in modern drug discovery. This compound is critical for medicinal chemists seeking to explore novel therapeutic agents, particularly within the fields of oncology and central nervous system (CNS) disorders. Its unique molecular architecture, featuring a brominated indole core linked to a piperidine carboxylate, makes it an essential building block for synthesizing targeted small molecule libraries and potential drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel bioactive molecules and investigational new drugs (INDs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for various therapeutic targets.
• Oncology Drug Discovery: Serves as a core scaffold for developing potential kinase inhibitors and other anti-cancer agents.
• CNS-Targeted Compound Libraries: Employed in the creation of compounds aimed at neurological and psychiatric disorders.
• Contract Research & Development (CRO): Supplied to CROs and academic institutions for custom synthesis and exploratory research projects.
• Process Chemistry & Scale-Up: Provides a defined starting point for developing robust, scalable synthetic routes under GMP conditions.

Basic Information

Product Name	Benzyl 4-((5-Bromo-1H-Indol-1-Yl)Methyl)Piperidine-1-Carboxylate
CAS No.	1808957-45-0
Molecular Formula	C22H23BrN2O2
Molecular Weight	427.34 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-4-[(5-bromo-1H-indol-1-yl)methyl]piperidine; 4-[(5-Bromo-1H-indol-1-yl)methyl]-1-(phenylmethoxy)carbonylpiperidine; Benzyl 4-[(5-bromo-1H-indol-1-yl)methyl]piperidine-1-carboxylate; 1-CBz-4-((5-Bromo-1H-indol-1-yl)methyl)piperidine; N-Cbz-4-((5-Bromo-1-indolyl)methyl)piperidine; Piperidine-1-carboxylic acid, 4-[(5-bromo-1H-indol-1-yl)methyl]-, benzyl ester
EINECS	Contact for details

Quality Control

Every batch of Benzyl 4-((5-Bromo-1H-Indol-1-Yl)Methyl)Piperidine-1-Carboxylate is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.