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Dnp-Peg4-Alcohol CAS NO 1807520-99-5


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CAS No.:1807520-99-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Dnp-Peg4-Alcohol CAS NO 1807520-99-5 is a specialized bifunctional chemical linker featuring a dinitrophenyl (DNP) group and a tetraethylene glycol (PEG4) spacer terminated with a primary alcohol. This compound is engineered to facilitate the conjugation of biomolecules, offering a controlled and stable linkage. It is primarily utilized by researchers and manufacturers in the fields of bioconjugation, proteomics, and pharmaceutical development for creating targeted drug delivery systems, diagnostic assays, and advanced research reagents.

Application

  • Bioconjugation Reagent: Used for coupling peptides, proteins, or antibodies to surfaces, nanoparticles, or other molecules via its reactive alcohol and DNP groups.
  • Proteomics Research: Serves as a versatile linker in the synthesis of activity-based probes (ABPs) or affinity tags for studying protein function and interactions.
  • Drug Delivery System Development: Incorporated into the design of antibody-drug conjugates (ADCs) or other targeted therapeutics to provide a cleavable or stable PEGylated linkage.
  • Diagnostic Assay Fabrication: Employed in the development of immunoassays and biosensors for attaching detection labels or capture molecules.
  • Material Science & Surface Functionalization: Applied to modify material surfaces with bioactive molecules for cell culture, tissue engineering, or sensor applications.
  • Crosslinking Agent: Acts as a heterobifunctional crosslinker for connecting two different entities in biochemical and biophysical studies.

Basic Information

Item Detail
Product Name Dnp-Peg4-Alcohol
CAS No. 1807520-99-5
Molecular Formula C19H30N2O9
Molecular Weight 430.45 g/mol
Synonyms 2,4-Dinitrophenyl-PEG4-alcohol; DNP-PEG4-OH; 2-[2-[2-[2-[2-(2,4-Dinitro-phenoxy)-ethoxy]-ethoxy]-ethoxy]-ethoxy]-ethanol; 1-(2,4-Dinitrophenoxy)-3,6,9,12-tetraoxapentadecan-15-ol; DNP tetraethylene glycol alcohol; DNP-PEG4-CH2CH2OH; DNP-PEG4 linker with terminal OH
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Quality Control

Our Dnp-Peg4-Alcohol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry, to ensure identity, potency, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP guidelines where applicable, supporting its use in research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. The product is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing desiccated at -20°C.

Specification

Item Specification
Appearance Yellow to orange viscous liquid or solid
Identification (HPLC) Conforms to reference standard
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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