Description

m-Peg5-Phosphonic Acid CAS NO 1807512-39-5 is a high-purity, heterobifunctional polyethylene glycol (PEG) derivative featuring a phosphonic acid group at one terminus and a methoxy group at the other. This compound is engineered to serve as a versatile linker and modifier, enabling the conjugation of biomolecules and materials to surfaces, particularly metal oxides, through its strong phosphonate anchoring chemistry. It is an essential reagent for researchers and manufacturers in the fields of bioconjugation, surface functionalization, and advanced material science, where precise control over interfacial properties is required.

Application

• Bioconjugation and Drug Delivery: Acts as a functional spacer to attach drugs, peptides, or proteins to nanoparticles or other carriers, enhancing solubility and stability.
• Surface Functionalization: Used to create anti-fouling, hydrophilic coatings on metal oxide surfaces (e.g., TiO2, SiO2, Fe3O4) for biosensor and diagnostic device development.
• Material Science: Serves as a key building block for modifying the surface properties of inorganic nanoparticles, quantum dots, and other nanomaterials.
• Chromatography and Separation Media: Can be immobilized onto stationary phases to create hydrophilic interaction liquid chromatography (HILIC) materials.
• Polymer Chemistry: Functions as a monomer or chain-transfer agent in the synthesis of functional polymers with tailored surface-active properties.
• Medical Device Coatings: Applied to implant surfaces to improve biocompatibility and reduce non-specific protein adsorption.

Basic Information

Product Name	m-Peg5-Phosphonic Acid
CAS No.	1807512-39-5
Molecular Formula	C16H35O10P
Molecular Weight	418.42 g/mol
Synonyms	mPEG5-phosphonic acid; Methoxy-PEG5-phosphonic acid; α-Methoxy-ω-phosphonato-penta(ethylene glycol); 2-[2-[2-[2-[2-(Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethylphosphonic acid; 3,6,9,12,15-Pentaoxaheptadecane-1,17-dioic acid, 17-phosphono-, 1-methyl ester; PEG-Phosphonate; HO-PEG5-OP(O)(OH)2; mPEG(5)-Phosphonic Acid
EINECS	Contact for details

Quality Control

Our m-Peg5-Phosphonic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry to ensure identity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your R&D and cGMP manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 90% (by titration)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.