Description

2,3-Dibromo-4-Fluorobenzyl Bromide is a high-purity, multi-functional halogenated benzyl bromide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which allows for selective and sequential functionalization, making it indispensable for creating complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used to construct advanced herbicide and fungicide molecules, leveraging the fluorine and bromine atoms for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized phosphine or N-heterocyclic carbene (NHC) ligands used in transition metal catalysis.
• Material Science Monomer: Employed in the creation of halogenated polymers and liquid crystals, where its structure imparts specific flame-retardant or optical properties.
• Cross-Coupling Reactions: An excellent substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to introduce complex aryl groups.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for studying biological processes due to its reactive benzyl bromide moiety.

Basic Information

Product Name	2,3-Dibromo-4-Fluorobenzyl Bromide
CAS No.	1806350-15-1
Molecular Formula	C7H4Br3F
Molecular Weight	370.82 g/mol
Synonyms	4-Fluoro-2,3-dibromobenzyl Bromide; (2,3-Dibromo-4-fluorophenyl)methyl Bromide; 1-(Bromomethyl)-2,3-dibromo-4-fluorobenzene; alpha,2,3-Tribromo-4-fluorotoluene; Benzene, 1-(bromomethyl)-2,3-dibromo-4-fluoro-; 2,3-Dibromo-4-fluoro-α-bromotoluene
EINECS	Contact for details

Quality Control

Our 2,3-Dibromo-4-Fluorobenzyl Bromide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.