Description

5-(Trifluoromethoxy)-1,3-Benzoxazol-2-Amine is a high-purity, advanced pharmaceutical intermediate and organic building block. This compound is valued for its unique benzoxazole core functionalized with a trifluoromethoxy group, which imparts desirable properties such as metabolic stability and enhanced lipophilicity for drug discovery. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. Our supply ensures consistent quality and reliable availability for critical development and scale-up processes.

Application

• Key intermediate in the research and synthesis of novel pharmaceutical candidates, particularly in oncology and CNS drug discovery.
• Building block for the development of advanced agrochemicals, including herbicides and fungicides.
• Precursor for the synthesis of functional materials and specialty chemicals requiring the benzoxazole scaffold.
• Used in academic and industrial research for studying structure-activity relationships (SAR) in medicinal chemistry.
• Component in the development of fluorescent dyes and molecular probes due to the benzoxazole structure.

Basic Information

Product Name	5-(Trifluoromethoxy)-1,3-Benzoxazol-2-Amine
CAS No.	1806318-94-4
Molecular Formula	C8H5F3N2O2
Molecular Weight	218.14 g/mol
Synonyms	2-Amino-5-(trifluoromethoxy)benzoxazole; 5-(Trifluoromethoxy)-2-benzoxazolamine; 1,3-Benzoxazol-2-amine, 5-(trifluoromethoxy)-; 2-Amino-5-(trifluoromethoxy)-1,3-benzoxazole; 5-Trifluoromethoxy-1,3-benzoxazol-2-ylamine; 1806318-94-4; 5-(Trifluoromethoxy)benzoxazol-2-amine
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethoxy)-1,3-Benzoxazol-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP standards for pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.