Description

1-Hydroxy-1,3-Dihydrobenzo[C][1,2]Oxaborole-5-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate featuring a unique benzooxaborole scaffold. This compound matters as a critical building block in modern medicinal chemistry, enabling the development of novel therapeutics with enhanced biological activity. It is primarily needed by research institutions and pharmaceutical manufacturers focused on creating innovative boron-containing drugs, particularly for applications in anti-infective and anti-inflammatory agents. Our supply ensures the stringent quality and consistency required for sensitive R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel boron-based drug candidates, especially protease inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new pharmacophores and optimize drug potency.
• API Development: Serves as a critical building block in the development of Active Pharmaceutical Ingredients (APIs) targeting bacterial and fungal infections.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme mechanisms and identify new therapeutic targets.
• Boronic Acid Derivative Synthesis: Utilized for further chemical modifications to create a library of derivatives for high-throughput screening.

Basic Information

Product Name	1-Hydroxy-1,3-Dihydrobenzo[C][1,2]Oxaborole-5-Carboxylic Acid
CAS No.	1801711-87-4
Molecular Formula	C8H7BO4
Molecular Weight	177.95 g/mol
Synonyms	5-Carboxy-1-hydroxy-1,3-dihydro-2,1-benzoxaborole; 1-Hydroxy-3H-2,1-benzoxaborole-5-carboxylic acid; 5-Carboxybenzooxaborol-1-ol; Benzoxaborole-5-carboxylic acid derivative; BDD-188001 (Research Code); CAS 1801711-87-4; 1,3-Dihydro-1-hydroxy-2,1-benzoxaborole-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Hydroxy-1,3-Dihydrobenzo[C][1,2]Oxaborole-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.