Description

5-Hydroxypyridine-3-Boronic Acid, Hcl is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, serving as a key intermediate in cross-coupling reactions like the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for drug discovery and advanced material development.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing pyridine and boronic acid pharmacophores.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic acid coupling partner for creating carbon-carbon bonds in complex organic synthesis.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require specific heterocyclic structures.
• Material Science & OLED Development: Acts as a building block for creating organic electronic materials, including ligands for metal-organic frameworks (MOFs) and emissive layers.
• Chemical Biology & Proteomics: Utilized in the design of molecular probes and inhibitors for studying enzyme function and protein interactions.
• Academic & Contract Research: A valuable reagent for university laboratories and CROs (Contract Research Organizations) engaged in medicinal chemistry and synthetic methodology projects.

Basic Information

Product Name	5-Hydroxypyridine-3-Boronic Acid, Hcl
CAS No.	1801408-19-4
Molecular Formula	C5H7BClNO3
Molecular Weight	174.38 g/mol
Synonyms	3-Borono-5-hydroxypyridine hydrochloride; (5-Hydroxypyridin-3-yl)boronic acid hydrochloride; 5-Hydroxy-3-pyridineboronic acid HCl; 5-Hydroxy-3-pyridinylboronic acid hydrochloride; 3-(5-Hydroxypyridinyl)boronic acid HCl salt; 5-Hydroxypyridine-3-boronic acid hydrochloride; 3-Boron-5-hydroxypyridine HCl
EINECS	Contact for details

Quality Control

Our 5-Hydroxypyridine-3-Boronic Acid, Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.