Description

(αr)-Tetrahydro-α-Phenyl-2H-Pyran-4-Methanol is a chiral, substituted tetrahydropyran derivative, a versatile and valuable building block in advanced organic synthesis. Its significance lies in its rigid, oxygen-containing heterocyclic structure, which serves as a key scaffold for constructing complex molecules with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, anti-infectives, and metabolic diseases.
• Agrochemical Research: Used as a precursor in developing new herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Ligand & Catalyst Development: Serves as a backbone for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: A monomer or modifier for synthesizing specialty polymers with unique thermal or optical properties.
• Flavor & Fragrance Chemistry: Potential intermediate for creating complex aroma chemicals and flavoring substances.
• Academic & Contract Research: A valuable reagent for methodological studies in synthetic organic chemistry and medicinal chemistry programs.

Basic Information

Item	Detail
Product Name	(αr)-Tetrahydro-α-Phenyl-2H-Pyran-4-Methanol
CAS No.	1800345-36-1
Molecular Formula	C12H16O2
Molecular Weight	192.26 g/mol
Synonyms	(αR)-Tetrahydro-α-phenyl-2H-pyran-4-methanol; (R)-Tetrahydro-α-phenyl-2H-pyran-4-methanol; 4-(Hydroxymethyl)-α-phenyl-tetrahydro-2H-pyran (enantiomer); Tetrahydro-α-phenyl-2H-pyran-4-methanol (Ar-isomer); (R)-4-(Hydroxymethyl)-α-phenyltetrahydro-2H-pyran; (R)-α-Phenyltetrahydro-2H-pyran-4-methanol; Chiral tetrahydropyran methanol derivative; Phenyl-substituted tetrahydropyran methanol
EINECS	Contact for details

Quality Control

Our (αr)-Tetrahydro-α-Phenyl-2H-Pyran-4-Methanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.