Description

1H-Indole-1-Carboxylic Acid, 2,3-Dihydro-5-Nitro-2-Oxo-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its specific indole-derived structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting complex biological pathways. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of novel drug candidates, especially those with indole-based scaffolds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes for discovering new bioactive molecules.
• API Development: Integral in the development and scale-up processes for new Active Pharmaceutical Ingredients (APIs) in preclinical and clinical stages.
• Chemical Synthesis: Employed in organic synthesis for introducing specific functional groups and constructing complex heterocyclic systems.
• Biochemical Research: Potential use as a reagent or probe in biochemical assays to study enzyme inhibition or receptor binding.

Basic Information

Product Name	1H-Indole-1-Carboxylic Acid, 2,3-Dihydro-5-Nitro-2-Oxo-, 1,1-Dimethylethyl Ester
CAS No.	1799838-87-1
Molecular Formula	C14H16N2O5
Molecular Weight	292.29 g/mol
Synonyms	tert-Butyl 5-nitro-2-oxo-2,3-dihydro-1H-indole-1-carboxylate; 1-(tert-Butoxycarbonyl)-5-nitroindolin-2-one; 5-Nitro-1-Boc-indolin-2-one; 1-Boc-5-nitroindolin-2-one; 5-Nitroindolin-2-one-1-carboxylic acid tert-butyl ester; 2,3-Dihydro-5-nitro-2-oxo-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; Boc-5-Nitro-oxindole
EINECS	Contact for details

Quality Control

Our production of 1H-Indole-1-Carboxylic Acid, 2,3-Dihydro-5-Nitro-2-Oxo-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials are characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.