Description

α-[1-[tert-Butyldimethylsilyloxy]-3-(Trimethylsilyl)-2-Propynyl]-α'-Ethynyl-α,α'-Dimethyl-1,1-Cyclopropanedimethanol is a highly functionalized, advanced organic intermediate featuring multiple silyl-protected hydroxyl and alkyne groups. This compound matters as a sophisticated building block for complex molecular synthesis, offering precise control over stereochemistry and functional group manipulation. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and complex natural product analogs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, particularly those requiring cyclopropane or advanced alkyne chemistry.
• Agrochemical Research: Used in developing novel pesticides and herbicides with specific steric and electronic properties.
• Material Science Precursor: Serves as a monomer or cross-linker for specialty polymers and dendrimers with tailored functionalities.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing challenging carbon frameworks and natural product analogs.
• Ligand Synthesis: Useful for creating complex chiral ligands for asymmetric catalysis.
• Probe and Diagnostic Agent Development: The alkyne groups make it suitable for "click chemistry" applications in bioconjugation and probe synthesis.

Basic Information

Item	Details
Product Name	α-[1-[tert-Butyldimethylsilyloxy]-3-(Trimethylsilyl)-2-Propynyl]-α'-Ethynyl-α,α'-Dimethyl-1,1-Cyclopropanedimethanol
CAS No.	1797112-19-6
Molecular Formula	C22H40O3Si2
Molecular Weight	408.73 g/mol
Synonyms	1,1-Cyclopropanedimethanol, α-[1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-(trimethylsilyl)-2-propyn-1-yl]-α'-ethynyl-α,α'-dimethyl-; α-[1-(tert-Butyldimethylsilyloxy)-3-(trimethylsilyl)prop-2-yn-1-yl]-α'-ethynyl-α,α'-dimethyl-1,1-cyclopropanedimethanol; TBDMS/TMS-protected cyclopropane dialkynol; Bis-silylated cyclopropane alkyne diol derivative.
EINECS	Contact for details

Quality Control

Our α-[1-[tert-Butyldimethylsilyloxy]-3-(Trimethylsilyl)-2-Propynyl]-α'-Ethynyl-α,α'-Dimethyl-1,1-Cyclopropanedimethanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and structural integrity, meeting the stringent requirements for advanced synthetic intermediates. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.