Description

(S)-1-Aminoindane-D3 is a chiral, deuterium-labeled derivative of 1-aminoindane, specifically designed for advanced research and development applications. This isotopically labeled compound serves as a critical internal standard and tracer in analytical chemistry, enabling precise quantification and metabolic pathway elucidation. It is primarily utilized by pharmaceutical researchers, analytical laboratories, and contract research organizations (CROs) engaged in drug discovery, pharmacokinetic studies, and forensic analysis.

Application

• Internal Standard for LC-MS/MS: Essential for accurate quantitative bioanalysis in pharmacokinetic (PK) and toxicokinetic (TK) studies due to its matched chemical structure and distinct mass shift.
• Metabolic Pathway Tracing: Used in drug metabolism and disposition (DMPK) research to track the fate of drug molecules and identify metabolites.
• Pharmaceutical Reference Standard: Serves as a high-purity certified reference material (CRM) for method development, validation, and quality control in pharmaceutical manufacturing.
• Forensic and Doping Control Analysis: Employed as a precision tool in forensic toxicology and anti-doping laboratories for the definitive identification and quantification of target analytes.
• Isotope Dilution Mass Spectrometry (IDMS): A key component in this gold-standard analytical technique for achieving highest accuracy in quantitative measurements.
• Neurological Research: Potential use in studying neurological pathways and receptors where the 1-aminoindane scaffold is pharmacologically active.

Basic Information

Product Name	(S)-1-Aminoindane-D3
CAS No.	1795787-04-0
Molecular Formula	C9H8D3N
Molecular Weight	135.21 g/mol (approx.)
Synonyms	(S)-1-Aminoindan-1,1,2,2,3,3-d6; (1S)-2,3-Dihydro-1H-inden-1-amine-1,1,2,2,3,3-d6; (S)-1-Aminoindane-d6; (S)-1-Amino-2,3-dihydro-1H-indene-D3; (S)-1-Indanamine-D3; Deuterated (S)-1-Aminoindane; (S)-1-Aminohydrindene-D3
EINECS	Contact for details

Quality Control

Every batch of (S)-1-Aminoindane-D3 is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as isotopic purity (D-enrichment), chemical purity (HPLC), chiral purity, and identity confirmation (NMR, MS). Our quality commitment supports compliance with relevant GLP and ISO guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.