Description

2-Bromo-3,4-Dimethoxy-Benzenemethanol-D3 is a deuterated derivative of a substituted benzenemethanol, serving as a crucial stable isotope-labeled building block for advanced chemical synthesis. This compound is specifically valued for its role in the development and analysis of pharmaceuticals and agrochemicals, where deuterium labeling is used to study metabolic pathways, improve pharmacokinetic profiles, and create internal standards for analytical methods. It is primarily utilized by research scientists and process chemists in pharmaceutical R&D, agrochemical development, and analytical contract research organizations.

Application

• Pharmaceutical Intermediate: A key deuterated synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs exploring structure-activity relationships.
• Metabolic Studies: Used as a stable isotope-labeled tracer in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of molecules in vivo using techniques like LC-MS.
• Internal Standard for Analytics: Essential for the preparation of high-precision internal standards in quantitative mass spectrometry, ensuring accurate bioanalysis and impurity profiling.
• Agrochemical Research: Employed in the synthesis of deuterated analogs of pesticides or herbicides to investigate environmental degradation and metabolic pathways.
• Material Science Research: Potential building block for creating specialized deuterated organic materials or ligands for catalytic systems where isotopic effects are studied.

Basic Information

Product Name	2-Bromo-3,4-Dimethoxy-Benzenemethanol-D3
CAS No.	1795029-54-7
Molecular Formula	C9H8D3BrO3
Molecular Weight	262.11 g/mol (approx.)
Synonyms	(3,4-Dimethoxy-2-bromophenyl)(hydroxy-D)methane-D2; 2-Bromo-3,4-dimethoxybenzyl-D3 alcohol; Benzenemethanol-D3, 2-bromo-3,4-dimethoxy-; (2-Bromo-3,4-dimethoxyphenyl)methanol-D3; α,α,α-trideuterio-2-Bromo-3,4-dimethoxybenzenemethanol
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality management systems to ensure high isotopic purity and chemical integrity. Each batch is characterized by advanced analytical techniques including NMR (¹H, ¹³C, ²H), mass spectrometry, and HPLC to confirm identity, chemical purity, and deuterium incorporation. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP and ISO compliant manufacturing for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Deuterium Incorporation (²H NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.