Description

n-Methylnitroacetamide-D3 is a deuterium-labeled isotopologue of n-methylnitroacetamide, serving as a critical internal standard and tracer in advanced analytical chemistry. Its primary value lies in enabling precise quantification and metabolic pathway elucidation through mass spectrometry, minimizing interference from endogenous compounds. This high-purity material is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and forensic science industries who require definitive analytical results.

Application

• Pharmaceutical Research & Development: Used as a stable isotope-labeled internal standard for the accurate bioanalysis and pharmacokinetic (PK) study of related drug candidates and metabolites via LC-MS/MS.
• Metabolomics & Biomarker Discovery: Acts as a tracer compound to investigate specific biochemical pathways and reaction mechanisms in complex biological systems.
• Forensic & Clinical Toxicology: Employed in method development and validation for the sensitive and specific detection of nitroacetamide derivatives in biological matrices.
• Agrochemical Analysis: Supports the residue analysis and environmental fate studies of related pesticidal compounds, ensuring regulatory compliance and safety.
• Chemical Synthesis Research: Serves as a deuterated building block or intermediate for synthesizing labeled analogs of more complex molecules for mechanistic studies.
• Quality Control & Reference Standards: Provides a certified reference material for calibrating analytical instruments and verifying method accuracy in contract research organizations (CROs) and manufacturing QC labs.

Basic Information

Product Name	n-Methylnitroacetamide-D3
CAS No.	1795020-80-2
Molecular Formula	C3H3D3N2O3
Molecular Weight	136.11 g/mol (approx.)
Synonyms	N-Methyl-2-nitroacetamide-d3; Deuterated N-Methylnitroacetamide; 2-Nitro-N-(methyl-d3)acetamide; Acetamide, 2-nitro-N-(methyl-d3)-; (Methyl-d3)nitroacetamide; Nitroacetamide-d3 N-methyl derivative; [2H3]-N-Methylnitroacetamide; N-Methyl-d3-nitroacetamide
EINECS	Contact for details

Quality Control

Our n-Methylnitroacetamide-D3 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high isotopic purity. Each lot undergoes comprehensive analysis, including NMR (1H, 13C) for structural confirmation and deuterium incorporation, HPLC for chemical purity, and Mass Spectrometry for isotopic enrichment verification. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.