Description

2-(4-Isobutylphenyl)Propyl-D3 Alcohol is a deuterated analog of a key pharmaceutical intermediate, where specific hydrogen atoms are replaced with the stable isotope deuterium. This deuteration is critical for enhancing metabolic stability and for use as an internal standard in advanced analytical techniques like mass spectrometry. It is primarily required by research institutions and pharmaceutical companies engaged in drug discovery, development, and bioanalytical method validation for non-steroidal anti-inflammatory drugs (NSAIDs).

Application

• As a deuterated internal standard for the accurate quantification of related active pharmaceutical ingredients (APIs) in bioanalytical studies using LC-MS/MS.
• In metabolic stability studies and pharmacokinetic (PK) research to investigate the deuterium kinetic isotope effect (DKIE) on drug molecules.
• For use in pharmaceutical research and development of novel deuterated drug candidates targeting improved therapeutic profiles.
• As a high-purity chemical reference standard in quality control laboratories for method development and validation.
• In isotope labeling research for mechanistic studies and tracer applications in medicinal chemistry.

Basic Information

Product Name	2-(4-Isobutylphenyl)Propyl-D3 Alcohol
CAS No.	1794979-83-1
Molecular Formula	C13H17D3O
Molecular Weight	207.33 g/mol (approx.)
Synonyms	2-(4-Isobutylphenyl)propan-1-ol-d3; Ibuprofen Alcohol-d3; 2-(p-Isobutylphenyl)propyl-d3 Alcohol; 2-[4-(2-Methylpropyl)phenyl]propyl-d3 Alcohol; Deuterated Ibuprofen Alcohol; (RS)-2-(4-Isobutylphenyl)propyl-1,1,2-d3 Alcohol; 1-(4-Isobutylphenyl)ethan-d3-ol
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality management to ensure high isotopic purity and chemical integrity, suitable for sensitive analytical applications. Each batch is characterized by advanced spectroscopic and chromatographic methods, including NMR and HPLC/GC-MS. A comprehensive Certificate of Analysis (COA) detailing assay, isotopic enrichment (D%), and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Isotopic Purity (D%)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.