Description

2-Amino-4'-Methyl-Acetophenone-D3 Hydrochloride is a high-purity, deuterium-labeled derivative of a key acetophenone intermediate. This compound is specifically valued for its role as a stable isotope-labeled internal standard in advanced analytical chemistry, ensuring precise and reliable quantification. It is an essential material for researchers and developers in the pharmaceutical and agrochemical sectors, particularly for method development, pharmacokinetic studies, and metabolite identification using mass spectrometry.

Application

• As a stable isotope-labeled internal standard for Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) analysis.
• Critical for quantitative bioanalysis in pharmaceutical research, including pharmacokinetic (PK) and pharmacodynamic (PD) studies.
• Use in metabolite identification and profiling to track drug distribution and breakdown pathways.
• Development and validation of regulatory-compliant analytical methods for drug substances and products.
• Application in isotope dilution mass spectrometry (IDMS) for achieving high accuracy in trace-level quantification.
• Research into the synthesis of novel, labeled compounds for use in mechanistic and degradation studies.

Basic Information

Product Name	2-Amino-4'-Methyl-Acetophenone-D3 Hydrochloride
CAS No.	1794977-34-6
Molecular Formula	C9H8D3ClNO
Molecular Weight	187.67 g/mol (approx.)
Synonyms	1-(4-Methylphenyl)-2-aminoethanone-D3 Hydrochloride; 2-Amino-1-(4-methylphenyl)ethanone-D3 Hydrochloride; 4'-Methyl-2-aminoacetophenone-D3 HCl; p-Methyl-2-aminoacetophenone-D3 Hydrochloride; Deuterated 2-Amino-4'-Methylacetophenone HCl; [D3]-2-Amino-4'-Methylacetophenone Hydrochloride; Stable Isotope Labeled Acetophenone Derivative
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-4'-Methyl-Acetophenone-D3 Hydrochloride is produced and tested under strict quality management protocols to ensure the high isotopic purity and chemical integrity required for sensitive analytical applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) providing detailed specifications for isotopic enrichment, chemical purity, and identity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D3)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.