Description

p-Cyanophenyl-D4 Methyl Ketone is a deuterium-labeled aromatic ketone, a high-purity isotopologue of p-cyanophenyl methyl ketone. This compound is specifically engineered for use as a critical internal standard and reference material in advanced analytical chemistry, ensuring unparalleled accuracy in quantitative analysis. It is primarily required by research and development laboratories in the pharmaceutical, agrochemical, and material science sectors for applications in mass spectrometry, NMR spectroscopy, and metabolic studies.

Application

• Internal Standard for LC-MS/MS: Essential for precise quantification in bioanalytical methods, pharmacokinetic studies, and drug metabolism research.
• NMR Spectroscopy Reference: Used as a deuterated shift and coupling constant reference in structural elucidation and reaction monitoring.
• Metabolite Tracing & Stable Isotope Labeling: A key precursor or tracer in metabolic pathway studies and the synthesis of deuterated drug candidates.
• Pharmaceutical Impurity Profiling: Serves as a reference standard for identifying and quantifying impurities and degradants in active pharmaceutical ingredients (APIs).
• Agrochemical Research: Employed in environmental fate studies and residue analysis of cyanophenyl-containing compounds.
• Material Science Research: Used in the development and analysis of advanced polymers and organic electronic materials where isotopic purity is critical.

Basic Information

Product Name	p-Cyanophenyl-D4 Methyl Ketone
CAS No.	1794964-28-5
Molecular Formula	C9H3D4NO
Molecular Weight	148.18 g/mol
Synonyms	1-[4-Cyanophenyl]-2,2,2,2-d4-ethanone; 4-Acetylbenzonitrile-d4; p-Acetylbenzonitrile-d4; 4-Cyanophenyl-D4 Methyl Ketone; Deuterated p-Cyanophenyl Methyl Ketone; 4-Cyanophenyl(CD3) ketone; (4-Cyanophenyl)(trideuteriomethyl)methanone; 4-Cyanophenyl methyl-d3 ketone
EINECS	Contact for details

Quality Control

Every batch of p-Cyanophenyl-D4 Methyl Ketone is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive characterization using NMR (¹H, ¹³C), Mass Spectrometry, and HPLC. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, isotopic enrichment, and other critical parameters to meet the exacting standards of analytical and synthetic laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.