Description

2-(2-Chloroethyl)-1-Methylpiperidine-D3 Hydrochloride is a deuterated derivative of a piperidine-based building block, featuring a chloroethyl side chain. This compound is specifically designed for use in pharmaceutical research and development, where its deuterium labeling provides significant advantages in metabolic and pharmacokinetic studies. It is primarily utilized by medicinal chemists and research scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active compounds and as a stable isotope-labeled internal standard in analytical applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of deuterated drug candidates for improved metabolic stability and pharmacokinetic profiles.
• Metabolic Studies: Used as a stable isotope-labeled tracer or internal standard in mass spectrometry (LC-MS/MS) for drug metabolism and pharmacokinetics (DMPK) research.
• Agrochemical Research: Serves as a precursor in the development of novel, labeled active ingredients for crop protection products.
• Chemical Biology Probes: Enables the creation of deuterium-labeled probes for studying biological pathways and protein interactions.
• Analytical Reference Standard: Provides a high-purity, isotopically labeled standard for accurate quantification in complex biological matrices.
• Neurological Research: Potential precursor for developing labeled analogs of compounds targeting neurological receptors.

Basic Information

Product Name	2-(2-Chloroethyl)-1-Methylpiperidine-D3 Hydrochloride
CAS No.	1794964-19-4
Molecular Formula	C8H13D3Cl2N
Molecular Weight	Contact for details
Synonyms	1-Methyl-2-(2-chloroethyl)piperidine-d3 hydrochloride; 2-(2-Chloroethyl)-1-methylpiperidine-2,6,6-d3 hydrochloride; 1-Methyl-2-(2-chloroethyl)piperidine-d3 HCl; N-Methyl-2-(2-chloroethyl)piperidine-d3 hydrochloride; Deuterated 2-Chloroethylmethylpiperidine HCl; 2-(2-Chloroethyl)-N-methylpiperidine-d3 hydrochloride; (2-Chloroethyl)methylpiperidine-d3 hydrochloride; 1-Methyl-2-(β-chloroethyl)piperidine-d3 hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(2-Chloroethyl)-1-Methylpiperidine-D3 Hydrochloride is manufactured under strict quality control protocols to ensure high chemical and isotopic purity suitable for research applications. Each batch is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry to confirm identity, chemical purity, and deuterium incorporation. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a desiccated environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.