Description

Rac 3,4-Bis(Benzyloxy)Phenylethylene Glycol-D5 is a deuterated derivative of a key benzyl-protected catechol intermediate, offering a stable isotopic label for advanced research and development. This compound is crucial for mechanistic studies, metabolic pathway tracing, and the synthesis of deuterated active pharmaceutical ingredients (APIs) where enhanced pharmacokinetic properties are desired. It serves as a vital building block for pharmaceutical chemists, analytical scientists, and research institutions engaged in drug discovery and development.

Application

• Deuterated Pharmaceutical Intermediate: Serves as a key labeled precursor in the synthesis of deuterated drug candidates for improved metabolic stability and bioavailability studies.
• Metabolic Tracer & Analytical Standard: Used in mass spectrometry and NMR-based studies to trace metabolic pathways and quantify metabolites in biological systems.
• Mechanistic Probe in Organic Synthesis: Employed in reaction mechanism elucidation, leveraging the kinetic isotope effect (KIE) of deuterium atoms.
• Precursor for Deuterated Catechol Derivatives: A protected intermediate for generating various deuterated catechols, which are important motifs in neuroscience and medicinal chemistry.
• Research & Development: Essential for academic and industrial R&D labs focusing on isotope chemistry, pharmacokinetics (PK), and pharmacodynamics (PD).

Basic Information

Product Name	Rac 3,4-Bis(Benzyloxy)Phenylethylene Glycol-D5
CAS No.	1794960-44-3
Molecular Formula	C22H17D5O4
Molecular Weight	~359.46 g/mol
Synonyms	1,2-Bis(3,4-bis(benzyloxy)phenyl)ethane-1,1,2,2,2-d5-diol; 3,4-Bis(benzyloxy)-α,α,β,β,β-d5-phenylethanediol; rac-3,4-Dibenzyloxyphenylethylene Glycol-d5; Deuterated 3,4-Dibenzyloxy Mandelic Acid Glycol; D5-3,4-Bis(Benzyloxy)Styrene Glycol; (rac)-3,4-Bis-O-benzyl-D5-phenylglycol; 1,2-Dideutero-1,1,2-trideuterio-1,2-bis(3,4-dibenzyloxyphenyl)ethane-1,2-diol
EINECS	Contact for details

Quality Control

Our Rac 3,4-Bis(Benzyloxy)Phenylethylene Glycol-D5 is manufactured under controlled conditions to ensure high isotopic and chemical purity, meeting the stringent requirements for research and development applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic purity (D-enrichment), chemical purity (HPLC), and identity confirmation (NMR, MS). We adhere to rigorous internal quality standards to guarantee batch-to-batch consistency and reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.