Description

2-(n-Acetoacetylamino)Ethanol-D4 is a deuterium-labeled derivative of 2-(n-Acetoacetylamino)ethanol, a key intermediate in organic synthesis. This compound is specifically valued for its role as a stable isotope-labeled internal standard in analytical chemistry, enabling precise quantification and method development. It is primarily required by research institutions and pharmaceutical companies engaged in advanced mass spectrometry (MS) and nuclear magnetic resonance (NMR) studies, where isotopic purity is critical for accurate results.

Application

• As a deuterated internal standard for the quantitative analysis of its non-labeled counterpart via LC-MS or GC-MS.
• Use in metabolic pathway tracing and pharmacokinetic studies within pharmaceutical R&D.
• Intermediate in the synthesis of deuterium-labeled pharmaceuticals and agrochemicals for research purposes.
• Application in NMR spectroscopy as a solvent or reagent to study molecular structure and dynamics.
• Used in the development and validation of analytical methods requiring high isotopic fidelity.
• Research chemical for studying reaction mechanisms where hydrogen/deuterium exchange is relevant.

Basic Information

Item	Detail
Product Name	2-(n-Acetoacetylamino)Ethanol-D4
CAS No.	1794960-21-6
Molecular Formula	C6H7D4NO3
Molecular Weight	149.18 g/mol (approx.)
Synonyms	2-(Acetoacetamido)ethanol-d4; N-(2-Hydroxyethyl)acetoacetamide-d4; 2-(N-Acetoacetylamino)ethanol-d4; Deuterated Acetoacetamide Ethanol; AAEE-d4; Acetoacetamide ethanol-d4; 2-(Acetoacetamido)ethan-d4-ol; [2H4]-2-(Acetoacetamido)ethanol
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced and tested to meet the exacting standards required for analytical and research applications. Each batch undergoes rigorous analysis to confirm isotopic purity (D-content) and chemical purity. Comprehensive Certificates of Analysis (COA) are provided, detailing results from NMR, MS, and HPLC analyses to ensure traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.