Description

2-[[(3,5-Dimethyl-2-Pyridinyl)Methyl]Thio]-6-Methoxy-1H-Benzimidazole-D3 is a deuterated derivative of a benzimidazole-based compound, serving as a critical stable isotope-labeled internal standard for precise analytical quantification. This high-purity material is essential for ensuring accuracy and reliability in sensitive mass spectrometry and chromatography-based methods. It is primarily utilized by pharmaceutical research and development laboratories, contract research organizations (CROs), and analytical testing facilities requiring definitive compound identification and quantification.

Application

• Internal Standard for LC-MS/MS: Used as a deuterium-labeled internal standard for the accurate quantification of its non-deuterated counterpart or related metabolites in complex biological matrices like plasma, serum, and urine.
• Pharmaceutical R&D: Critical in drug metabolism and pharmacokinetics (DMPK) studies, bioanalytical method development, and validation to ensure data integrity and regulatory compliance.
• Clinical Research: Enables precise measurement of drug concentrations in patient samples during clinical trials, supporting pharmacokinetic profiling and therapeutic drug monitoring.
• Metabolite Identification: Aids in the identification and structural elucidation of drug metabolites by providing a stable isotopic reference point.
• Quality Control in Manufacturing: Employed in the quality control laboratories of API manufacturers to monitor process-related impurities and ensure batch-to-batch consistency.
• Forensic and Toxicology Analysis: Provides a reliable reference for the detection and quantification of specific compounds in forensic science and toxicological screenings.

Basic Information

Product Name	2-[[(3,5-Dimethyl-2-Pyridinyl)Methyl]Thio]-6-Methoxy-1H-Benzimidazole-D3
CAS No.	1794938-78-5
Molecular Formula	C₁₆H₁₅D₃N₃OS
Molecular Weight	~297.4 g/mol
Synonyms	6-Methoxy-2-[[(3,5-dimethyl-2-pyridinyl)methyl]thio]-1H-benzimidazole-d3; Deuterated Omeprazole Impurity/Related Substance; 2-(((3,5-Dimethylpyridin-2-yl)methyl)thio)-6-methoxy-1H-benzo[d]imidazole-d3; 6-Methoxy-2-(((3,5-dimethylpyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole-d3; Benzimidazole-d3 derivative; Stable Isotope Labeled Benzimidazole; (D3)-2-[[(3,5-Dimethyl-2-pyridinyl)methyl]thio]-6-methoxy-1H-benzimidazole
EINECS	Contact for details

Quality Control

Our deuterated standards are manufactured under strict quality control protocols to ensure the highest isotopic purity and chemical integrity. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) is provided, detailing isotopic enrichment (typically ≥98 atom % D), chemical purity, and confirming identity and purity. We support compliance with GMP/GLP guidelines for research and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. Keep the container in a dry, cool, and well-ventilated place. For long-term storage, consider storing under inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (NMR/MS)	≥98 atom % D
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.