Description

1,7-Bis[4-Hydroxy-3-(Trideuteriomethoxy)Phenyl]Heptane-3,5-Dione is a deuterated derivative of a natural curcuminoid analog, offering enhanced metabolic stability and utility as a sophisticated research tool. This compound is valued for its application in advanced pharmaceutical research, particularly in drug discovery and development where isotopic labeling is critical for pharmacokinetic and metabolic studies. It is primarily targeted at research institutions, pharmaceutical R&D laboratories, and specialty chemical manufacturers engaged in developing next-generation therapeutic agents and analytical standards.

Application

• Pharmaceutical Research & Drug Discovery: Serves as a deuterium-labeled internal standard or tracer in mass spectrometry for quantitative bioanalysis and ADME (Absorption, Distribution, Metabolism, and Excretion) studies.
• Metabolic Pathway Investigation: Used to elucidate metabolic pathways and stability of curcuminoid-based drug candidates by tracking the deuterium label.
• High-Purity Reference Standard: Employed in analytical laboratories for method development, validation, and quality control of related active pharmaceutical ingredients (APIs).
• Biochemical Probe Development: Acts as a key intermediate or probe in researching inflammation, oncology, and neurodegenerative disease pathways.
• Isotope Chemistry & Synthesis: Utilized as a building block in the synthesis of more complex deuterated molecules for research purposes.

Basic Information

Product Name	1,7-Bis[4-Hydroxy-3-(Trideuteriomethoxy)Phenyl]Heptane-3,5-Dione
CAS No.	1794898-13-7
Molecular Formula	C23H22D6O6
Molecular Weight	406.50 g/mol
Synonyms	Deuterated Curcumin Derivative; 1,7-Bis(4-Hydroxy-3-(trideuteriomethoxy)phenyl)-3,5-heptanedione; 1,7-Bis(4-Hydroxy-3-(CD3O)phenyl)heptane-3,5-dione; Bis-Deuteromethoxy Curcumin Analog; (3E,5E)-3,5-Bis(4-Hydroxy-3-(trideuteriomethoxy)benzylidene)piperidin-4-one precursor; Hexadeutero Curcuminoid; Labeled Diferuloylmethane Derivative; CAS 1794898-13-7
EINECS	Contact for details

Quality Control

Our 1,7-Bis[4-Hydroxy-3-(Trideuteriomethoxy)Phenyl]Heptane-3,5-Dione is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and isotopic enrichment verification, to ensure compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and isotopic purity is provided with every shipment to guarantee traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under inert atmosphere for long-term stability. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.