Description

α-(Aminomethyl)-p-Methylbenzyl-D3 Alcohol is a deuterated organic compound featuring an aminomethyl and a benzyl alcohol functional group on a methyl-substituted aromatic ring. This deuterium-labeled analog is a critical building block for the synthesis of isotopically labeled pharmaceuticals and advanced materials, offering enhanced metabolic stability and traceability in research. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and analytical chemistry sectors for drug discovery, metabolic studies, and the development of internal standards for mass spectrometry.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of deuterium-labeled active pharmaceutical ingredients (APIs) to study pharmacokinetics and metabolism.
• Metabolic Research: Used as a stable isotope-labeled tracer in drug metabolism and pharmacokinetics (DMPK) studies to track molecular pathways.
• Mass Spectrometry Standards: Serves as an internal standard for the accurate quantification of non-labeled analogs in LC-MS and GC-MS analytical methods.
• Agrochemical Development: Employed in the synthesis of novel, isotopically labeled pesticides and herbicides for environmental fate studies.
• Material Science Research: A precursor for creating deuterated polymers or liquid crystals with modified physical properties for specialized applications.
• Chemical Biology Probes: Facilitates the development of labeled probes for investigating biological mechanisms and protein interactions.

Basic Information

Product Name	α-(Aminomethyl)-p-Methylbenzyl-D3 Alcohol
CAS No.	1794884-99-3
Molecular Formula	C10H12D3NO
Molecular Weight	166.25 g/mol (approx.)
Synonyms	4-(Aminomethyl)-α-(trideuteriomethyl)benzenemethanol; p-Methyl-α-(aminomethyl)benzyl-d3 Alcohol; (4-(Aminomethyl)phenyl)(trideuteriomethyl)methanol; 1-(4-(Aminomethyl)phenyl)ethanol-d3; Deuterated Benzyl Alcohol Aminomethyl Derivative; α-(Aminomethyl)-4-methylbenzyl-d3 Alcohol; Benzenemethanol, 4-(aminomethyl)-α-(trideuteriomethyl)-
EINECS	Contact for details

Quality Control

Every batch of α-(Aminomethyl)-p-Methylbenzyl-D3 Alcohol is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and synthesis. A Certificate of Analysis (COA) detailing purity, isotopic enrichment, and impurity profiles by NMR, HPLC, and MS is supplied with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isotopic Enrichment (D-content, MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.