Description

2'',4''-Dihydroxy-2-Benzoylbenzoic Acid-D4 is a deuterated derivative of a key benzophenone-based intermediate, offering a stable isotopic label for advanced research and development. This high-purity compound is essential for applications requiring precise tracking and analysis in metabolic and pharmacokinetic studies. It is primarily utilized by pharmaceutical researchers, analytical laboratories, and manufacturers of specialty chemicals for developing deuterated drug candidates and analytical standards.

Application

• As a stable isotopic internal standard for the accurate quantification of its non-deuterated counterpart in complex biological matrices using LC-MS/MS.
• In the synthesis of deuterated pharmaceutical compounds, where the incorporation of deuterium can alter metabolic pathways and improve drug profiles.
• For metabolic pathway tracing and mechanistic studies in preclinical pharmaceutical research.
• In the development and calibration of high-precision analytical reference materials and certified standards.
• As a specialized intermediate in organic synthesis and medicinal chemistry research focused on benzophenone scaffolds.
• For use in nuclear magnetic resonance (NMR) spectroscopy as a tool to simplify spectral analysis.

Basic Information

Item	Detail
Product Name	2'',4''-Dihydroxy-2-Benzoylbenzoic Acid-D4
CAS No.	1794883-65-0
Molecular Formula	C14H4D4O5
Molecular Weight	~ 264.23 g/mol
Synonyms	2-Benzoyl-2',4'-dihydroxybenzoic Acid-d4; 2,4-Dihydroxy-2-benzoylbenzoic Acid-d4; 2-Carboxy-2',4'-dihydroxybenzophenone-d4; DHB-d4; Benzophenone-2,4-dicarboxylic Acid-d4 Derivative; [D4]-2,4-DHBBA; Deuterated Benzoyl Salicylic Acid Derivative
EINECS	Contact for details

Quality Control

Every batch of 2'',4''-Dihydroxy-2-Benzoylbenzoic Acid-D4 is produced and analyzed under strict quality management protocols. We ensure high isotopic purity and chemical purity through advanced analytical techniques including NMR, HPLC, and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified and kept in a low-humidity environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.