Description

5-Nitro-1H-Imidazole-1-Ethanol-D4 is a high-purity, deuterated derivative of a key nitroimidazole intermediate, offering a stable isotopic label for advanced research and development. This compound is critical for applications requiring precise molecular tracking and metabolic studies due to its deuterium substitution. It is primarily utilized by pharmaceutical researchers, analytical laboratories, and chemical manufacturers involved in the synthesis of novel drug candidates, diagnostic agents, and as a reference standard.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of deuterated active pharmaceutical ingredients (APIs) and prodrugs.
• Metabolic Research & Tracer Studies: Used as a stable isotope-labeled internal standard in mass spectrometry for pharmacokinetic and metabolic pathway analysis.
• Analytical Reference Standard: Serves as a certified reference material (CRM) for method development, validation, and quality control in analytical laboratories.
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) studies and the development of novel therapeutic agents, particularly in antimicrobial and antiparasitic domains.
• Isotope Labeling: Provides a deuterium-labeled synthon for creating more complex labeled compounds for use in NMR spectroscopy and other detection techniques.

Basic Information

Product Name	5-Nitro-1H-Imidazole-1-Ethanol-D4
CAS No.	1794791-19-7
Molecular Formula	C5H3D4N3O3
Molecular Weight	160.14 g/mol (approx.)
Synonyms	2-(5-Nitro-1H-imidazol-1-yl)ethanol-d4; 1-(2-Hydroxyethyl)-5-nitroimidazole-d4; 5-Nitro-1-(2-hydroxyethyl)imidazole-d4; Deuterated Metronidazole Impurity/Intermediate; 5-Nitroimidazole-1-ethanol-d4; [1,1,2,2-D4]-2-(5-Nitro-1H-imidazol-1-yl)ethan-1-ol
EINECS	Contact for details

Quality Control

Our 5-Nitro-1H-Imidazole-1-Ethanol-D4 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and mass spectrometry, to ensure high isotopic purity and chemical identity. Certificates of Analysis (COA) detailing isotopic enrichment (D-content), chemical purity, and impurity profiles are provided to guarantee reproducibility and reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.