Description

1-Benzyl-2,2,5,5-Tetradeuterio-3-Methylpiperazine is a deuterium-labeled derivative of a key piperazine scaffold, offering a stable isotopic marker for advanced research and development. This compound is critical for applications requiring precise metabolic and pharmacokinetic studies, where tracking molecular pathways is essential. It is primarily utilized by pharmaceutical researchers, analytical laboratories, and chemical manufacturers focused on drug discovery, process chemistry, and the development of deuterated active pharmaceutical ingredients (APIs).

Application

• Deuterated Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of deuterium-labeled drug candidates to enhance metabolic stability and study drug behavior.
• Metabolic Pathway Tracer: Used in mass spectrometry and NMR-based studies to track and quantify the absorption, distribution, metabolism, and excretion (ADME) of compounds.
• Internal Standard for Analytical Chemistry: Provides a high-purity reference standard for quantitative LC-MS and GC-MS analysis, ensuring accurate measurement in complex matrices.
• Isotope Labeling Research: Enables fundamental research in chemical reaction mechanisms and the development of novel labeling techniques.
• Process Chemistry & Scale-up: Supports the development and optimization of synthetic routes for deuterated compounds at various scales.

Basic Information

Product Name	1-Benzyl-2,2,5,5-Tetradeuterio-3-Methylpiperazine
CAS No.	1794752-53-6
Molecular Formula	C₁₂H₁₄D₄N₂
Molecular Weight	~194.30 g/mol
Synonyms	1-Benzyl-3-methylpiperazine-2,2,5,5-d4; 3-Methyl-1-(phenylmethyl)piperazine-2,2,5,5-d4; 1-Benzyl-3-methylpiperazine-d4; Deuterated 1-Benzyl-3-methylpiperazine; 1-Bn-3-Me-piperazine-d4; Bn-MPZ-d4; (2,2,5,5-Tetradeuterio-3-methylpiperazin-1-yl)methylbenzene
EINECS	Contact for details

Quality Control

Our 1-Benzyl-2,2,5,5-Tetradeuterio-3-Methylpiperazine is manufactured under strict quality systems to ensure high isotopic purity and chemical integrity. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chemical purity, isotopic enrichment (D-content), and impurity profiles. We adhere to cGMP principles where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and analytical standard production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.