Description

1-tert-Butyl 6-Methyl 5-Bromoindoline-1,6-Dicarboxylate is a high-value, multi-functional chemical intermediate characterized by its indoline core and strategically positioned bromine and carboxylate protecting groups. This compound matters for its role as a versatile building block in complex organic synthesis, enabling the construction of advanced molecular architectures. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those containing functionalized indoline or indole scaffolds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated structure.
• Material Science Research: Acts as a monomer or building block for the development of specialty polymers and advanced organic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in cross-coupling reactions and heterocyclic chemistry.
• Fine Chemical Production: Utilized in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	1-tert-Butyl 6-Methyl 5-Bromoindoline-1,6-Dicarboxylate
CAS No.	1788044-06-3
Molecular Formula	C16H20BrNO4
Molecular Weight	370.24 g/mol
Synonyms	5-Bromo-1,6-indoledicarboxylic acid 1-tert-butyl 6-methyl ester; 5-Bromoindoline-1,6-dicarboxylic acid 1-tert-butyl 6-methyl ester; Methyl 5-bromo-1-(tert-butoxycarbonyl)indoline-6-carboxylate; 1-Boc-6-methyl 5-bromoindoline-1,6-dicarboxylate; 5-Bromo-1-N-Boc-indoline-6-carboxylic acid methyl ester; tert-Butyl 5-bromo-6-(methoxycarbonyl)indoline-1-carboxylate
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl 6-Methyl 5-Bromoindoline-1,6-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly sealed due to potential sensitivity to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.