Description

(1R,2R,4S)-Rel-Methyl 7-Azabicyclo[2.2.1]Heptane-2-Carboxylate Oxalate is a high-purity, chiral bicyclic amine derivative that serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. Its value lies in its rigid, three-dimensional scaffold, which is essential for imparting specific biological activity and stereochemical control in final drug molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly in the areas of central nervous system (CNS) agents and complex small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs) targeting neurological disorders.
• Medicinal Chemistry Research: Used as a constrained scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Asymmetric Synthesis: Employed as a chiral auxiliary or building block to introduce stereogenic centers in complex organic molecules.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in asymmetric catalysis.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	(1R,2R,4S)-Rel-Methyl 7-Azabicyclo[2.2.1]Heptane-2-Carboxylate Oxalate
CAS No.	1788041-49-5
Molecular Formula	C9H13NO2 • C2H2O4
Molecular Weight	273.24 g/mol
Synonyms	Methyl (1R,2R,4S)-rel-7-azabicyclo[2.2.1]heptane-2-carboxylate oxalate; Methyl 7-azabicyclo[2.2.1]heptane-2-carboxylate oxalate (rel-(1R,2R,4S)-isomer); 7-Azabicyclo[2.2.1]heptane-2-carboxylic acid, methyl ester, (1R,2R,4S)-rel-, oxalate; rel-(1R,2R,4S)-Methyl 7-azabicyclo[2.2.1]heptane-2-carboxylate oxalate; Bicyclic amine ester oxalate salt; 7-Azanorbornane derivative.
EINECS	Contact for details

Quality Control

Our (1R,2R,4S)-Rel-Methyl 7-Azabicyclo[2.2.1]Heptane-2-Carboxylate Oxalate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every lot and provided upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.