Description

(R)-2-(Piperidin-3-Yl)Isoindolin-1-One is a high-purity chiral building block and pharmaceutical intermediate. This compound is of significant interest for its utility in the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in drug discovery and development, particularly for central nervous system (CNS) and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic agents.
• Asymmetric Synthesis: Serves as a versatile chiral scaffold for constructing complex molecules with defined stereochemistry.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	(R)-2-(Piperidin-3-Yl)Isoindolin-1-One
CAS No.	1786495-37-1
Molecular Formula	C13H16N2O
Molecular Weight	216.28 g/mol
Synonyms	(3R)-2-(3-Piperidinyl)-1H-isoindol-1-one; (R)-2-(Piperidin-3-yl)isoindolin-1-one; 1H-Isoindol-1-one, 2-(3-piperidinyl)-, (3R)-; (R)-2-(3-Piperidyl)isoindolin-1-one; (R)-2-(Piperidin-3-yl)-2,3-dihydro-1H-isoindol-1-one; (R)-2-(3-Piperidinyl)-1H-isoindol-1-one; (R)-2-(Piperidin-3-yl)isoindolinone; (R)-2-(3-Piperidyl)-1H-isoindol-1-one
EINECS	Contact for details

Quality Control

Our (R)-2-(Piperidin-3-Yl)Isoindolin-1-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All batches are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.