Description

2-(3-Chloro-4-Fluorophenyl)-2,2-Difluoroethanol CAS NO 1785261-10-0 is a high-purity fluorinated aromatic alcohol building block, essential for advanced organic synthesis. This compound is valued for its unique difluoroethanol moiety attached to a halogenated phenyl ring, enabling precise molecular modifications. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine atoms enhance biological activity, metabolic stability, and lipophilicity.
• Liquid Crystal Material Precursor: Serves as a building block for fluorinated liquid crystal compounds used in high-performance displays.
• Polymer Chemistry: Employed to introduce fluorinated side chains into specialty polymers, improving their chemical resistance, thermal stability, and surface properties.
• Organic Electronics: Acts as an intermediate in the synthesis of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research & Development: A versatile reagent for exploring new fluorination methodologies and constructing complex molecular architectures in academic and industrial labs.

Basic Information

Product Name	2-(3-Chloro-4-Fluorophenyl)-2,2-Difluoroethanol
CAS No.	1785261-10-0
Molecular Formula	C8H5ClF3O
Molecular Weight	218.57 g/mol
Synonyms	2,2-Difluoro-2-(3-chloro-4-fluorophenyl)ethanol; 1-(3-Chloro-4-fluorophenyl)-2,2-difluoroethan-1-ol; 3-Chloro-4-fluoro-α,α-difluorobenzeneethanol; (3-Chloro-4-fluorophenyl)difluoromethyl carbinol; α,α-Difluoro-3-chloro-4-fluorobenzeneethanol
EINECS	Contact for details

Quality Control

Our 2-(3-Chloro-4-Fluorophenyl)-2,2-Difluoroethanol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.