Description

8-Fluoroisoquinolin-4-Amine CAS NO 1785091-04-4 is a high-purity, advanced pharmaceutical intermediate characterized by its unique fluorinated isoquinoline scaffold. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of targeted small-molecule drugs and investigational new chemical entities (NCEs).
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization programs due to its fluorinated heterocyclic structure.
• Agrochemical Development: Serves as a building block for creating novel active ingredients with potential herbicidal or pesticidal properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Organic Synthesis: Acts as a versatile fluorinated amine component in various cross-coupling and functionalization reactions.

Basic Information

Product Name	8-Fluoroisoquinolin-4-Amine
CAS No.	1785091-04-4
Molecular Formula	C9H7FN2
Molecular Weight	162.16 g/mol
Synonyms	4-Amino-8-fluoroisoquinoline; 8-Fluoro-4-isoquinolinamine; 8-Fluoro-isoquinolin-4-ylamine; 8-Fluoro-4-aminoisoquinoline; 1785091-04-4; 8-Fluoro-4-isoquinolamine; 4-Isoquinolinamine, 8-fluoro-
EINECS	Contact for details

Quality Control

Our 8-Fluoroisoquinolin-4-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.